@Sabb84
Let's start from the top.
The first goal here is to make your game
not crash, right? In Steam, "delete local files" for the game, then go into the SR4 folder and delete anything that's left. Now go back to Steam and install the game again. Does it run and not crash?
Next you want to get mods working. Ultimate Disintegrator is just a very simple mod with very obvious effects. Install that mod, and see if it has taken effect.
Finally, if you want to use multiple mods that change the same files, you need to merge the files, which will both 1) stop the crashing that would happen if you simply dumped them all in and 2) make them work, which they wouldn't if you simply dumped them all in. Using Stream2Update from Minimaul's tools in the Tools Releases forum will be necessary if they share asm_pc files, because you can't merge those.