If you download the mission replay mod v2 from Idolninja, there will be a file called sr3_city.lua in the SR3 directory. Open it with your favourite editor (I prefer Notepad++) and find this:
function sr3_city_main()
end
In between the function and the end line, place this:
spawn_override_change_hood_alternate_spawning("HOOD_ZOMBIE", false)
city_zone_swap("chemcrash", false)
city_zone_swap("zombies", false)
city_zone_swap("lockdown", false)
city_zone_swap("stag", false)
spawn_override_change_hood_alternate_spawning("HOOD_DT_02", false)
spawn_override_change_hood_alternate_spawning("HOOD_DT_03", false)
If you want to restore the statue, add this too:
city_zone_swap("rubble", false)
NOTE:
This might make some missions be buggy or uncompletable, I only tried it on my complete save and haven't had time to replay all the missions.