Totally! That would be so awesome! Then you get the fun based missions in Steelport, and the more dark, realistic missions in Stilwater. A super plot twist! The boss got gravely injured on that plane and the only way to save her ( My boss is female... ) was to put her mind to a machine so she wouldn't go braindead or something, and in her mind she created Steelport. In the realworld, Johnny, Shaundi and Pierce are working around to clock to bring the boss back out of there before she completely looses her mind. And now Aliens start to invade steelport, she is the president of the US... she is clearly going bat shit insane. so they have to get her out of there before she dies in her own mind and goes braindead forever!!
So after EtD she is pulled out finally and you have to get used to the real world again, but for some reason she took the experiences with her she gained in Steelport. So they recreate Saints Flow that actually does work in the real world ( Bat shit insane, you said? Phuh! ) as an added extra. Plus all the crazy combat moved and such, they'll recreate the Dub Step weapon, and all the other over the top weapons she thought up in Steelport.
Then you have a Matrix meets Inception scenario. Could be fun.
So after EtD she is pulled out finally and you have to get used to the real world again, but for some reason she took the experiences with her she gained in Steelport. So they recreate Saints Flow that actually does work in the real world ( Bat shit insane, you said? Phuh! ) as an added extra. Plus all the crazy combat moved and such, they'll recreate the Dub Step weapon, and all the other over the top weapons she thought up in Steelport.
Then you have a Matrix meets Inception scenario. Could be fun.